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Mary K. Estes
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Mary K. Estes : ウィキペディア英語版
Mary K. Estes

Mary K. Estes, Ph.D is a professor at Baylor College of Medicine in Houston, Texas. Her courses include microbiology, and virology; she is also the co-director of the Transitional Biology and Molecular Medicine Graduate Program at Baylor College of Medicine.〔(【引用サイトリンク】url=https://www.bcm.edu/people/view/b211e57a-ffed-11e2-be68-080027880ca6/902f3f0a-382f-11e3-9de7-005056b104be )〕 There are two main viruses that her research is based on, rotaviruses and noroviruses. The main goal of her research are to study how the viral proteins interact with the receptors of the intestinal cells; they are also looking into different ways to deliver virus-like particles to prevent these viruses from causing infections.〔 Estes has achieved many awards and recognition in her time as a virologist. She is also a member of multiple foundations and professional societies.
==Contributions to virology==

Estes has studied rotaviruses and noroviruses. Although rotaviruses can infect animals, the research Estes performs concerns its effects on children. In the 2009 article ''Rotaviruses: from pathogenesis to vaccination'' Estes explains the life-threatening side effects of rotavirus infection and the vaccinations that are now being used as a preventative measure. Efforts, by others to develop a successful vaccine against the virus started in the 1980s. Two vaccines were eventually developed —RotaTeq and Rotarix; however, there has been some concern about their safety due to an small increased risk of intussusception. Estes' research group is credited with discovering a novel enterotoxin involved in rotavirus pathology, as well as the effect of histoblood group antigens on an individuals susceptibility to norowalk virus infection. Estes’s laboratory continues to research the molecular mechanisms involved in the pathology of gastrointestinal viruses using recombinant virus-like particles to probe their structure and function.〔 She is also, through collaboration, working on vaccine development for the noroviruses that she studies.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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